In the era of personalized medicine, GLIOscreen drug screening service can serve to identify (subgroups of) glioma patients that will benefit from specific treatments. Stratification of patients in phase II/III clinical studies according to predicted response may increase the probability of demonstrating therapeutic activity of novel agents or treatment regimens. Molecular data (RNA/DNA) of parental tumors can be analyzed in the context of response to a specific treatment, allowing the identification of (a set of) genes that predict response (“predictor profiles”).